| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-10-07 | Los Angeles Rams () | 26 | Seattle Seahawks (7-9) | 17 | Rams | 11 |
| 2021-10-10 | New York Jets (11-5) | 20 | Atlanta Falcons (13-3) | 27 | Falcons | 5 |
| 2021-10-10 | Philadelphia Eagles (10-6) | 21 | Carolina Panthers (2-14) | 18 | Panthers | 10 |
| 2021-10-10 | Green Bay Packers (10-6) | 25 | Cincinnati Bengals (4-12) | 22 | Bengals | 1 |
| 2021-10-10 | New England Patriots (14-2) | 25 | Houston Texans (6-10) | 22 | Patriots | 7 |
| 2021-10-10 | Tennessee Titans (6-10) | 37 | Jacksonville Jaguars (8-8) | 19 | Titans | 9 |
| 2021-10-10 | Detroit Lions (6-10) | 17 | Minnesota Vikings (6-10) | 19 | Vikings | 15 |
| 2021-10-10 | Denver Broncos (4-12) | 19 | Pittsburgh Steelers (12-4) | 27 | Broncos | 8 |
| 2021-10-10 | Miami Dolphins (7-9) | 17 | Tampa Bay Buccaneers (10-6) | 45 | Buccaneers | 16 |
| 2021-10-10 | New Orleans Saints (11-5) | 33 | Washington Commanders (6-10) | 22 | Saints | 6 |
| 2021-10-10 | Cleveland Browns (5-11) | 42 | Los Angeles Chargers (9-7) | 47 | Chargers | 2 |
| 2021-10-10 | Chicago Bears (11-5) | 20 | Las Vegas Raiders () | 9 | Raiders | 13 |
| 2021-10-10 | San Francisco 49ers (6-10) | 10 | Arizona Cardinals (5-11) | 17 | 49ers | 3 |
| 2021-10-10 | New York Giants (10-6) | 20 | Dallas Cowboys (6-10) | 44 | Cowboys | 14 |
| 2021-10-10 | Buffalo Bills (4-12) | 38 | Kansas City Chefs (10-6) | 20 | Chefs | 4 |
| 2021-10-11 | Indianapolis Colts (10-6) | 25 | Baltimore Ravens (12-4) | 31 | Ravens | 12 |
| Totals | 10/16 | 97/136 | ||||
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