| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2010-10-24 | Philadelphia Eagles (11-6) | 19 | Tennessee Titans (6-11) | 37 | - | - |
| 2010-10-24 | Cincinnati Bengals (9-8) | 32 | Atlanta Falcons (7-10) | 39 | - | - |
| 2010-10-24 | Cleveland Browns (11-6) | 30 | New Orleans Saints (9-8) | 17 | - | - |
| 2010-10-24 | Pittsburgh Steelers (10-7) | 23 | Miami Dolphins (11-6) | 22 | - | - |
| 2010-10-24 | St. Louis Rams () | 17 | Tampa Bay Buccaneers (9-8) | 18 | - | - |
| 2010-10-24 | San Francisco 49ers (12-5) | 20 | Carolina Panthers (2-15) | 23 | - | - |
| 2010-10-24 | Washington Commanders (4-13) | 17 | Chicago Bears (7-10) | 14 | - | - |
| 2010-10-24 | Jacksonville Jaguars (9-8) | 20 | Kansas City Chefs (11-6) | 42 | - | - |
| 2010-10-24 | Buffalo Bills (11-6) | 34 | Baltimore Ravens (13-4) | 37 | - | - |
| 2010-10-24 | Arizona Cardinals (4-13) | 10 | Seattle Seahawks (9-8) | 22 | - | - |
| 2010-10-24 | Oakland Raiders () | 59 | Denver Broncos (8-9) | 14 | - | - |
| 2010-10-24 | New England Patriots (4-13) | 23 | Los Angeles Chargers (5-12) | 20 | - | - |
| 2010-10-24 | Minnesota Vikings (7-10) | 24 | Green Bay Packers (9-8) | 28 | - | - |
| 2010-10-25 | New York Giants (6-11) | 41 | Dallas Cowboys (12-5) | 35 | - | - |
| Totals | 0/0 | 0/0 | ||||
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