| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-11-18 | New England Patriots (10-7) | 25 | Atlanta Falcons (7-10) | 0 | Patriots | 8 |
| 2021-11-21 | Indianapolis Colts (9-8) | 41 | Buffalo Bills (11-6) | 15 | Bills | 10 |
| 2021-11-21 | Washington Commanders (7-10) | 27 | Carolina Panthers (5-12) | 21 | Panthers | 7 |
| 2021-11-21 | Baltimore Ravens (8-9) | 16 | Chicago Bears (6-11) | 13 | Ravens | 11 |
| 2021-11-21 | Detroit Lions (3-13-1) | 10 | Cleveland Browns (8-9) | 13 | Browns | 14 |
| 2021-11-21 | San Francisco 49ers (10-7) | 30 | Jacksonville Jaguars (3-14) | 10 | 49ers | 9 |
| 2021-11-21 | Green Bay Packers (13-4) | 31 | Minnesota Vikings (8-9) | 34 | Packers | 6 |
| 2021-11-21 | Miami Dolphins (9-8) | 24 | New York Jets (4-13) | 17 | Dolphins | 5 |
| 2021-11-21 | New Orleans Saints (9-8) | 29 | Philadelphia Eagles (9-8) | 40 | Saints | 3 |
| 2021-11-21 | Houston Texans (4-13) | 22 | Tennessee Titans (12-5) | 13 | Titans | 12 |
| 2021-11-21 | Cincinnati Bengals (10-7) | 32 | Las Vegas Raiders (10-7) | 13 | Bengals | 4 |
| 2021-11-21 | Dallas Cowboys (12-5) | 9 | Kansas City Chefs (12-5) | 19 | Chefs | 2 |
| 2021-11-21 | Arizona Cardinals (11-6) | 23 | Seattle Seahawks (7-10) | 13 | Cardinals | 13 |
| 2021-11-21 | Pittsburgh Steelers (9-7-1) | 37 | Los Angeles Chargers (9-8) | 41 | Chargers | 15 |
| 2021-11-22 | New York Giants (4-13) | 10 | Tampa Bay Buccaneers (13-4) | 30 | Buccaneers | 16 |
| Totals | 10/15 | 97/135 | ||||
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