| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-11-25 | Chicago Bears (5-12) | 16 | Detroit Lions (15-2) | 14 | - | - |
| 2021-11-25 | Las Vegas Raiders (4-13) | 36 | Dallas Cowboys (7-10) | 33 | - | - |
| 2021-11-25 | Buffalo Bills (13-4) | 31 | New Orleans Saints (5-12) | 6 | - | - |
| 2021-11-28 | Pittsburgh Steelers (10-7) | 10 | Cincinnati Bengals (9-8) | 41 | - | - |
| 2021-11-28 | New York Jets (5-12) | 21 | Houston Texans (10-7) | 14 | - | - |
| 2021-11-28 | Tampa Bay Buccaneers (10-7) | 38 | Indianapolis Colts (8-9) | 31 | - | - |
| 2021-11-28 | Atlanta Falcons (8-9) | 21 | Jacksonville Jaguars (4-13) | 14 | - | - |
| 2021-11-28 | Carolina Panthers (5-12) | 10 | Miami Dolphins (8-9) | 33 | - | - |
| 2021-11-28 | Tennessee Titans (3-14) | 13 | New England Patriots (4-13) | 36 | - | - |
| 2021-11-28 | Philadelphia Eagles (14-3) | 7 | New York Giants (3-14) | 13 | - | - |
| 2021-11-28 | Los Angeles Chargers (11-6) | 13 | Denver Broncos (10-7) | 28 | - | - |
| 2021-11-28 | Los Angeles Rams (10-7) | 28 | Green Bay Packers (11-6) | 36 | - | - |
| 2021-11-28 | Minnesota Vikings (14-3) | 26 | San Francisco 49ers (6-11) | 34 | - | - |
| 2021-11-28 | Cleveland Browns (3-14) | 10 | Baltimore Ravens (12-5) | 16 | - | - |
| 2021-11-29 | Seattle Seahawks (10-7) | 15 | Washington Commanders (12-5) | 17 | - | - |
| Totals | 0/0 | 0/0 | ||||
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