| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2010-09-19 | Baltimore Ravens (9-7) | 10 | Cincinnati Bengals (7-9) | 15 | - | - |
| 2010-09-19 | Tampa Bay Buccaneers (5-11) | 20 | Carolina Panthers (11-5) | 7 | - | - |
| 2010-09-19 | Buffalo Bills (9-7) | 7 | Green Bay Packers (7-9) | 34 | - | - |
| 2010-09-19 | Miami Dolphins (6-10) | 14 | Minnesota Vikings (13-3) | 10 | - | - |
| 2010-09-19 | Chicago Bears (5-11) | 27 | Dallas Cowboys (9-7) | 20 | - | - |
| 2010-09-19 | Philadelphia Eagles (13-3) | 35 | Detroit Lions (9-7) | 32 | - | - |
| 2010-09-19 | Arizona Cardinals (8-8) | 7 | Atlanta Falcons (10-6) | 41 | - | - |
| 2010-09-19 | Kansas City Chefs (10-6) | 16 | Cleveland Browns (0-16) | 14 | - | - |
| 2010-09-19 | Pittsburgh Steelers (13-3) | 19 | Tennessee Titans (9-7) | 11 | - | - |
| 2010-09-19 | Seattle Seahawks (9-7) | 14 | Denver Broncos (5-11) | 31 | - | - |
| 2010-09-19 | St. Louis Rams () | 14 | Oakland Raiders (6-10) | 16 | - | - |
| 2010-09-19 | New England Patriots (13-3) | 14 | New York Jets (5-11) | 28 | - | - |
| 2010-09-19 | Houston Texans (4-12) | 30 | Washington Commanders (7-9) | 27 | - | - |
| 2010-09-19 | Jacksonville Jaguars (10-6) | 13 | Los Angeles Chargers (9-7) | 38 | - | - |
| 2010-09-19 | New York Giants (3-13) | 14 | Indianapolis Colts (4-12) | 38 | - | - |
| 2010-09-20 | New Orleans Saints (11-5) | 25 | San Francisco 49ers (6-10) | 22 | - | - |
| Totals | 0/0 | 0/0 | ||||
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