| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2010-10-17 | Cleveland Browns (4-12) | 10 | Pittsburgh Steelers (12-4) | 28 | - | - |
| 2010-10-17 | New Orleans Saints (13-3) | 31 | Tampa Bay Buccaneers (4-12) | 6 | - | - |
| 2010-10-17 | Miami Dolphins (6-10) | 23 | Green Bay Packers (15-1) | 20 | - | - |
| 2010-10-17 | Los Angeles Chargers (8-8) | 17 | St. Louis Rams (2-14) | 20 | - | - |
| 2010-10-17 | Baltimore Ravens (12-4) | 20 | New England Patriots (13-3) | 23 | - | - |
| 2010-10-17 | Kansas City Chefs (7-9) | 31 | Houston Texans (10-6) | 35 | - | - |
| 2010-10-17 | Detroit Lions (10-6) | 20 | New York Giants (9-7) | 28 | - | - |
| 2010-10-17 | Atlanta Falcons (10-6) | 17 | Philadelphia Eagles (8-8) | 31 | - | - |
| 2010-10-17 | Seattle Seahawks (7-9) | 23 | Chicago Bears (8-8) | 20 | - | - |
| 2010-10-17 | Oakland Raiders (8-8) | 9 | San Francisco 49ers (13-3) | 17 | - | - |
| 2010-10-17 | New York Jets (8-8) | 24 | Denver Broncos (8-8) | 20 | - | - |
| 2010-10-17 | Dallas Cowboys (8-8) | 21 | Minnesota Vikings (3-13) | 24 | - | - |
| 2010-10-17 | Indianapolis Colts (2-14) | 27 | Washington Commanders (5-11) | 24 | - | - |
| 2010-10-18 | Tennessee Titans (9-7) | 30 | Jacksonville Jaguars (5-11) | 3 | - | - |
| Totals | 0/0 | 0/0 | ||||
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