| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-09-23 | Carolina Panthers (5-11) | 24 | Houston Texans (4-12) | 9 | - | - |
| 2021-09-26 | Washington Commanders (7-9) | 21 | Buffalo Bills (13-3) | 43 | - | - |
| 2021-09-26 | Chicago Bears (8-8) | 6 | Cleveland Browns (11-5) | 26 | - | - |
| 2021-09-26 | Baltimore Ravens (11-5) | 19 | Detroit Lions (5-11) | 17 | - | - |
| 2021-09-26 | Arizona Cardinals (8-8) | 31 | Jacksonville Jaguars (1-15) | 19 | - | - |
| 2021-09-26 | Los Angeles Chargers (7-9) | 30 | Kansas City Chefs (14-2) | 24 | - | - |
| 2021-09-26 | New Orleans Saints (12-4) | 28 | New England Patriots (7-9) | 13 | - | - |
| 2021-09-26 | Atlanta Falcons (4-12) | 17 | New York Giants (6-10) | 14 | - | - |
| 2021-09-26 | Cincinnati Bengals (4-11-1) | 24 | Pittsburgh Steelers (12-4) | 10 | - | - |
| 2021-09-26 | Indianapolis Colts (11-5) | 16 | Tennessee Titans (11-5) | 25 | - | - |
| 2021-09-26 | New York Jets (2-14) | 0 | Denver Broncos (5-11) | 26 | - | - |
| 2021-09-26 | Miami Dolphins (10-6) | 28 | Las Vegas Raiders () | 31 | - | - |
| 2021-09-26 | Tampa Bay Buccaneers (11-5) | 24 | Los Angeles Rams (10-6) | 34 | - | - |
| 2021-09-26 | Seattle Seahawks (12-4) | 17 | Minnesota Vikings (7-9) | 30 | - | - |
| 2021-09-26 | Green Bay Packers (13-3) | 30 | San Francisco 49ers (6-10) | 28 | - | - |
| 2021-09-27 | Philadelphia Eagles (4-11-1) | 21 | Dallas Cowboys (6-10) | 41 | - | - |
| Totals | 0/0 | 0/0 | ||||
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