| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-09-16 | New York Giants (4-13) | 29 | Washington Commanders (7-10) | 30 | Commanders | 1 |
| 2021-09-19 | New Orleans Saints (9-8) | 7 | Carolina Panthers (5-12) | 26 | Panthers | 9 |
| 2021-09-19 | Cincinnati Bengals (10-7) | 17 | Chicago Bears (6-11) | 20 | Bengals | 4 |
| 2021-09-19 | Houston Texans (4-13) | 21 | Cleveland Browns (8-9) | 31 | Browns | 12 |
| 2021-09-19 | Los Angeles Rams (12-5) | 27 | Indianapolis Colts (9-8) | 24 | Rams | 5 |
| 2021-09-19 | Denver Broncos (7-10) | 23 | Jacksonville Jaguars (3-14) | 13 | Broncos | 14 |
| 2021-09-19 | Buffalo Bills (11-6) | 35 | Miami Dolphins (9-8) | 0 | Dolphins | 3 |
| 2021-09-19 | New England Patriots (10-7) | 25 | New York Jets (4-13) | 6 | Patriots | 13 |
| 2021-09-19 | San Francisco 49ers (10-7) | 17 | Philadelphia Eagles (9-8) | 11 | 49ers | 7 |
| 2021-09-19 | Las Vegas Raiders (10-7) | 26 | Pittsburgh Steelers (9-7-1) | 17 | Steelers | 8 |
| 2021-09-19 | Minnesota Vikings (8-9) | 33 | Arizona Cardinals (11-6) | 34 | Cardinals | 6 |
| 2021-09-19 | Atlanta Falcons (7-10) | 25 | Tampa Bay Buccaneers (13-4) | 48 | Buccaneers | 15 |
| 2021-09-19 | Dallas Cowboys (12-5) | 20 | Los Angeles Chargers (9-8) | 17 | Cowboys | 2 |
| 2021-09-19 | Tennessee Titans (12-5) | 33 | Seattle Seahawks (7-10) | 30 | Seahawks | 11 |
| 2021-09-19 | Kansas City Chefs (12-5) | 35 | Baltimore Ravens (8-9) | 36 | Chefs | 10 |
| 2021-09-20 | Detroit Lions (3-13-1) | 17 | Green Bay Packers (13-4) | 35 | Packers | 16 |
| Totals | 11/16 | 100/136 | ||||
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