| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-09-23 | Carolina Panthers (15-1) | 24 | Houston Texans (9-7) | 9 | Panthers | 14 |
| 2021-09-26 | Washington Commanders (9-7) | 21 | Buffalo Bills (8-8) | 43 | Bills | 9 |
| 2021-09-26 | Chicago Bears (6-10) | 6 | Cleveland Browns (3-13) | 26 | Browns | 10 |
| 2021-09-26 | Baltimore Ravens (5-11) | 19 | Detroit Lions (7-9) | 17 | Ravens | 15 |
| 2021-09-26 | Arizona Cardinals (13-3) | 31 | Jacksonville Jaguars (5-11) | 19 | Cardinals | 11 |
| 2021-09-26 | Los Angeles Chargers (4-12) | 30 | Kansas City Chefs (11-5) | 24 | Chefs | 7 |
| 2021-09-26 | New Orleans Saints (7-9) | 28 | New England Patriots (12-4) | 13 | Patriots | 6 |
| 2021-09-26 | Atlanta Falcons (8-8) | 17 | New York Giants (6-10) | 14 | Giants | 8 |
| 2021-09-26 | Cincinnati Bengals (12-4) | 24 | Pittsburgh Steelers (10-6) | 10 | Steelers | 5 |
| 2021-09-26 | Indianapolis Colts (8-8) | 16 | Tennessee Titans (3-13) | 25 | Titans | 13 |
| 2021-09-26 | New York Jets (10-6) | 0 | Denver Broncos (12-4) | 26 | Broncos | 16 |
| 2021-09-26 | Miami Dolphins (6-10) | 28 | Las Vegas Raiders () | 31 | Raiders | 12 |
| 2021-09-26 | Tampa Bay Buccaneers (6-10) | 24 | Los Angeles Rams () | 34 | Rams | 1 |
| 2021-09-26 | Seattle Seahawks (10-6) | 17 | Minnesota Vikings (11-5) | 30 | Vikings | 2 |
| 2021-09-26 | Green Bay Packers (10-6) | 30 | San Francisco 49ers (5-11) | 28 | 49ers | 4 |
| 2021-09-27 | Philadelphia Eagles (7-9) | 21 | Dallas Cowboys (4-12) | 41 | Cowboys | 3 |
| Totals | 11/16 | 106/136 | ||||
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