| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-09-09 | Dallas Cowboys (8-8) | 29 | Tampa Bay Buccaneers (4-12) | 31 | - | - |
| 2021-09-12 | Philadelphia Eagles (10-6) | 32 | Atlanta Falcons (4-12) | 6 | - | - |
| 2021-09-12 | Pittsburgh Steelers (8-8) | 23 | Buffalo Bills (6-10) | 16 | - | - |
| 2021-09-12 | New York Jets (8-8) | 14 | Carolina Panthers (12-4) | 19 | - | - |
| 2021-09-12 | Minnesota Vikings (5-10-1) | 24 | Cincinnati Bengals (11-5) | 27 | - | - |
| 2021-09-12 | San Francisco 49ers (12-4) | 41 | Detroit Lions (7-9) | 33 | - | - |
| 2021-09-12 | Jacksonville Jaguars (4-12) | 21 | Houston Texans (2-14) | 37 | - | - |
| 2021-09-12 | Seattle Seahawks (13-3) | 28 | Indianapolis Colts (11-5) | 16 | - | - |
| 2021-09-12 | Arizona Cardinals (10-6) | 38 | Tennessee Titans (7-9) | 13 | - | - |
| 2021-09-12 | Los Angeles Chargers (9-7) | 20 | Washington Commanders (3-13) | 16 | - | - |
| 2021-09-12 | Cleveland Browns (4-12) | 29 | Kansas City Chefs (11-5) | 33 | - | - |
| 2021-09-12 | Miami Dolphins (8-8) | 17 | New England Patriots (12-4) | 16 | - | - |
| 2021-09-12 | Green Bay Packers (8-7-1) | 3 | New Orleans Saints (11-5) | 38 | - | - |
| 2021-09-12 | Denver Broncos (13-3) | 27 | New York Giants (7-9) | 13 | - | - |
| 2021-09-12 | Chicago Bears (8-8) | 14 | Los Angeles Rams () | 34 | - | - |
| 2021-09-13 | Baltimore Ravens (8-8) | 27 | Las Vegas Raiders () | 33 | - | - |
| Totals | 0/0 | 0/0 | ||||
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