| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-10-07 | Los Angeles Rams (11-5) | 26 | Seattle Seahawks (9-7) | 17 | - | - |
| 2021-10-10 | New York Jets (5-11) | 20 | Atlanta Falcons (10-6) | 27 | - | - |
| 2021-10-10 | Philadelphia Eagles (13-3) | 21 | Carolina Panthers (11-5) | 18 | - | - |
| 2021-10-10 | Green Bay Packers (7-9) | 25 | Cincinnati Bengals (7-9) | 22 | - | - |
| 2021-10-10 | New England Patriots (13-3) | 25 | Houston Texans (4-12) | 22 | - | - |
| 2021-10-10 | Tennessee Titans (9-7) | 37 | Jacksonville Jaguars (10-6) | 19 | - | - |
| 2021-10-10 | Detroit Lions (9-7) | 17 | Minnesota Vikings (13-3) | 19 | - | - |
| 2021-10-10 | Denver Broncos (5-11) | 19 | Pittsburgh Steelers (13-3) | 27 | - | - |
| 2021-10-10 | Miami Dolphins (6-10) | 17 | Tampa Bay Buccaneers (5-11) | 45 | - | - |
| 2021-10-10 | New Orleans Saints (11-5) | 33 | Washington Commanders (7-9) | 22 | - | - |
| 2021-10-10 | Cleveland Browns (0-16) | 42 | Los Angeles Chargers (9-7) | 47 | - | - |
| 2021-10-10 | Chicago Bears (5-11) | 20 | Las Vegas Raiders () | 9 | - | - |
| 2021-10-10 | San Francisco 49ers (6-10) | 10 | Arizona Cardinals (8-8) | 17 | - | - |
| 2021-10-10 | New York Giants (3-13) | 20 | Dallas Cowboys (9-7) | 44 | - | - |
| 2021-10-10 | Buffalo Bills (9-7) | 38 | Kansas City Chefs (10-6) | 20 | - | - |
| 2021-10-11 | Indianapolis Colts (4-12) | 25 | Baltimore Ravens (9-7) | 31 | - | - |
| Totals | 0/0 | 0/0 | ||||
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