| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-11-25 | Chicago Bears (10-6) | 16 | Detroit Lions (4-12) | 14 | Bears | 10 |
| 2021-11-25 | Las Vegas Raiders () | 36 | Dallas Cowboys (8-8) | 33 | Cowboys | 16 |
| 2021-11-25 | Buffalo Bills (6-10) | 31 | New Orleans Saints (7-9) | 6 | Bills | 14 |
| 2021-11-28 | Pittsburgh Steelers (8-8) | 10 | Cincinnati Bengals (10-6) | 41 | Bengals | 13 |
| 2021-11-28 | New York Jets (6-10) | 21 | Houston Texans (12-4) | 14 | Texans | 6 |
| 2021-11-28 | Tampa Bay Buccaneers (7-9) | 38 | Indianapolis Colts (11-5) | 31 | Buccaneers | 8 |
| 2021-11-28 | Atlanta Falcons (13-3) | 21 | Jacksonville Jaguars (2-14) | 14 | Falcons | 4 |
| 2021-11-28 | Carolina Panthers (7-9) | 10 | Miami Dolphins (7-9) | 33 | Panthers | 7 |
| 2021-11-28 | Tennessee Titans (6-10) | 13 | New England Patriots (12-4) | 36 | Patriots | 15 |
| 2021-11-28 | Philadelphia Eagles (4-12) | 7 | New York Giants (9-7) | 13 | Eagles | 12 |
| 2021-11-28 | Los Angeles Chargers (7-9) | 13 | Denver Broncos (13-3) | 28 | Chargers | 5 |
| 2021-11-28 | Los Angeles Rams () | 28 | Green Bay Packers (11-5) | 36 | Rams | 3 |
| 2021-11-28 | Minnesota Vikings (10-6) | 26 | San Francisco 49ers (11-4-1) | 34 | 49ers | 9 |
| 2021-11-28 | Cleveland Browns (5-11) | 10 | Baltimore Ravens (10-6) | 16 | Ravens | 11 |
| 2021-11-29 | Seattle Seahawks (11-5) | 15 | Washington Commanders (10-6) | 17 | Commanders | 2 |
| Totals | 9/15 | 86/135 | ||||
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