| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-11-25 | Chicago Bears (7-10) | 16 | Detroit Lions (12-5) | 14 | Bears | 5 |
| 2021-11-25 | Las Vegas Raiders (8-9) | 36 | Dallas Cowboys (12-5) | 33 | Cowboys | 16 |
| 2021-11-25 | Buffalo Bills (11-6) | 31 | New Orleans Saints (9-8) | 6 | Bills | 13 |
| 2021-11-28 | Pittsburgh Steelers (10-7) | 10 | Cincinnati Bengals (9-8) | 41 | Bengals | 8 |
| 2021-11-28 | New York Jets (7-10) | 21 | Houston Texans (10-7) | 14 | Texans | 9 |
| 2021-11-28 | Tampa Bay Buccaneers (9-8) | 38 | Indianapolis Colts (9-8) | 31 | Buccaneers | 10 |
| 2021-11-28 | Atlanta Falcons (7-10) | 21 | Jacksonville Jaguars (9-8) | 14 | Falcons | 7 |
| 2021-11-28 | Carolina Panthers (2-15) | 10 | Miami Dolphins (11-6) | 33 | Panthers | 6 |
| 2021-11-28 | Tennessee Titans (6-11) | 13 | New England Patriots (4-13) | 36 | Patriots | 11 |
| 2021-11-28 | Philadelphia Eagles (11-6) | 7 | New York Giants (6-11) | 13 | Eagles | 15 |
| 2021-11-28 | Los Angeles Chargers (5-12) | 13 | Denver Broncos (8-9) | 28 | Chargers | 12 |
| 2021-11-28 | Los Angeles Rams (10-7) | 28 | Green Bay Packers (9-8) | 36 | Packers | 2 |
| 2021-11-28 | Minnesota Vikings (7-10) | 26 | San Francisco 49ers (12-5) | 34 | 49ers | 3 |
| 2021-11-28 | Cleveland Browns (11-6) | 10 | Baltimore Ravens (13-4) | 16 | Ravens | 14 |
| 2021-11-29 | Seattle Seahawks (9-8) | 15 | Washington Commanders (4-13) | 17 | Commanders | 4 |
| Totals | 10/15 | 77/135 | ||||
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