| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2010-10-10 | Tampa Bay Buccaneers (8-9) | 24 | Cincinnati Bengals (6-11) | 21 | - | - |
| 2010-10-10 | Atlanta Falcons (8-9) | 20 | Cleveland Browns (5-12) | 10 | - | - |
| 2010-10-10 | New York Giants (4-13) | 34 | Houston Texans (12-5) | 10 | - | - |
| 2010-10-10 | Kansas City Chefs (6-11) | 9 | Indianapolis Colts (8-9) | 19 | - | - |
| 2010-10-10 | Green Bay Packers (9-7-1) | 13 | Washington Commanders (5-12) | 16 | - | - |
| 2010-10-10 | Jacksonville Jaguars (13-4) | 36 | Buffalo Bills (12-5) | 26 | - | - |
| 2010-10-10 | Denver Broncos (14-3) | 17 | Baltimore Ravens (8-9) | 31 | - | - |
| 2010-10-10 | Chicago Bears (11-6) | 23 | Carolina Panthers (8-9) | 6 | - | - |
| 2010-10-10 | St. Louis Rams () | 6 | Detroit Lions (9-8) | 44 | - | - |
| 2010-10-10 | New Orleans Saints (6-11) | 20 | Arizona Cardinals (3-14) | 30 | - | - |
| 2010-10-10 | Los Angeles Chargers (11-6) | 27 | Oakland Raiders () | 35 | - | - |
| 2010-10-10 | Tennessee Titans (3-14) | 34 | Dallas Cowboys (7-9-1) | 27 | - | - |
| 2010-10-10 | Philadelphia Eagles (11-6) | 27 | San Francisco 49ers (12-5) | 24 | - | - |
| 2010-10-11 | Minnesota Vikings (9-8) | 20 | New York Jets (3-14) | 29 | - | - |
| Totals | 0/0 | 0/0 | ||||
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