| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-11-25 | Chicago Bears (12-4) | 16 | Detroit Lions (6-10) | 14 | - | - |
| 2021-11-25 | Las Vegas Raiders () | 36 | Dallas Cowboys (10-6) | 33 | - | - |
| 2021-11-25 | Buffalo Bills (6-10) | 31 | New Orleans Saints (13-3) | 6 | - | - |
| 2021-11-28 | Pittsburgh Steelers (9-6-1) | 10 | Cincinnati Bengals (6-10) | 41 | - | - |
| 2021-11-28 | New York Jets (4-12) | 21 | Houston Texans (11-5) | 14 | - | - |
| 2021-11-28 | Tampa Bay Buccaneers (5-11) | 38 | Indianapolis Colts (10-6) | 31 | - | - |
| 2021-11-28 | Atlanta Falcons (7-9) | 21 | Jacksonville Jaguars (5-11) | 14 | - | - |
| 2021-11-28 | Carolina Panthers (7-9) | 10 | Miami Dolphins (7-9) | 33 | - | - |
| 2021-11-28 | Tennessee Titans (9-7) | 13 | New England Patriots (11-5) | 36 | - | - |
| 2021-11-28 | Philadelphia Eagles (9-7) | 7 | New York Giants (5-11) | 13 | - | - |
| 2021-11-28 | Los Angeles Chargers (12-4) | 13 | Denver Broncos (6-10) | 28 | - | - |
| 2021-11-28 | Los Angeles Rams (13-3) | 28 | Green Bay Packers (6-9-1) | 36 | - | - |
| 2021-11-28 | Minnesota Vikings (8-7-1) | 26 | San Francisco 49ers (4-12) | 34 | - | - |
| 2021-11-28 | Cleveland Browns (7-8-1) | 10 | Baltimore Ravens (10-6) | 16 | - | - |
| 2021-11-29 | Seattle Seahawks (10-6) | 15 | Washington Commanders (7-9) | 17 | - | - |
| Totals | 0/0 | 0/0 | ||||
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