| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-10-14 | Tampa Bay Buccaneers (4-12) | 28 | Philadelphia Eagles (10-6) | 22 | - | - |
| 2021-10-17 | Miami Dolphins (8-8) | 20 | Jacksonville Jaguars (4-12) | 23 | - | - |
| 2021-10-17 | Los Angeles Chargers (9-7) | 6 | Baltimore Ravens (8-8) | 34 | - | - |
| 2021-10-17 | Minnesota Vikings (5-10-1) | 34 | Carolina Panthers (12-4) | 28 | - | - |
| 2021-10-17 | Green Bay Packers (8-7-1) | 24 | Chicago Bears (8-8) | 14 | - | - |
| 2021-10-17 | Cincinnati Bengals (11-5) | 34 | Detroit Lions (7-9) | 11 | - | - |
| 2021-10-17 | Houston Texans (2-14) | 3 | Indianapolis Colts (11-5) | 31 | - | - |
| 2021-10-17 | Los Angeles Rams () | 38 | New York Giants (7-9) | 11 | - | - |
| 2021-10-17 | Kansas City Chefs (11-5) | 31 | Washington Commanders (3-13) | 13 | - | - |
| 2021-10-17 | Arizona Cardinals (10-6) | 37 | Cleveland Browns (4-12) | 14 | - | - |
| 2021-10-17 | Las Vegas Raiders () | 34 | Denver Broncos (13-3) | 24 | - | - |
| 2021-10-17 | Dallas Cowboys (8-8) | 35 | New England Patriots (12-4) | 29 | - | - |
| 2021-10-17 | Seattle Seahawks (13-3) | 20 | Pittsburgh Steelers (8-8) | 23 | - | - |
| 2021-10-18 | Buffalo Bills (6-10) | 31 | Tennessee Titans (7-9) | 34 | - | - |
| Totals | 0/0 | 0/0 | ||||
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