| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2010-10-03 | New York Jets (2-14) | 38 | Buffalo Bills (13-3) | 14 | - | - |
| 2010-10-03 | Seattle Seahawks (12-4) | 3 | St. Louis Rams () | 20 | - | - |
| 2010-10-03 | Carolina Panthers (5-11) | 14 | New Orleans Saints (12-4) | 16 | - | - |
| 2010-10-03 | Detroit Lions (5-11) | 26 | Green Bay Packers (13-3) | 28 | - | - |
| 2010-10-03 | Cincinnati Bengals (4-11-1) | 20 | Cleveland Browns (11-5) | 23 | - | - |
| 2010-10-03 | Baltimore Ravens (11-5) | 17 | Pittsburgh Steelers (12-4) | 14 | - | - |
| 2010-10-03 | Denver Broncos (5-11) | 26 | Tennessee Titans (11-5) | 20 | - | - |
| 2010-10-03 | San Francisco 49ers (6-10) | 14 | Atlanta Falcons (4-12) | 16 | - | - |
| 2010-10-03 | Indianapolis Colts (11-5) | 28 | Jacksonville Jaguars (1-15) | 31 | - | - |
| 2010-10-03 | Houston Texans (4-12) | 31 | Oakland Raiders (8-8) | 24 | - | - |
| 2010-10-03 | Washington Commanders (7-9) | 17 | Philadelphia Eagles (4-11-1) | 12 | - | - |
| 2010-10-03 | Arizona Cardinals (8-8) | 10 | Los Angeles Chargers (7-9) | 41 | - | - |
| 2010-10-03 | Chicago Bears (8-8) | 3 | New York Giants (6-10) | 17 | - | - |
| 2010-10-04 | New England Patriots (7-9) | 41 | Miami Dolphins (10-6) | 14 | - | - |
| Totals | 0/0 | 0/0 | ||||
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