| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-11-25 | Chicago Bears (6-10) | 16 | Detroit Lions (7-9) | 14 | - | - |
| 2021-11-25 | Las Vegas Raiders () | 36 | Dallas Cowboys (4-12) | 33 | - | - |
| 2021-11-25 | Buffalo Bills (8-8) | 31 | New Orleans Saints (7-9) | 6 | - | - |
| 2021-11-28 | Pittsburgh Steelers (10-6) | 10 | Cincinnati Bengals (12-4) | 41 | - | - |
| 2021-11-28 | New York Jets (10-6) | 21 | Houston Texans (9-7) | 14 | - | - |
| 2021-11-28 | Tampa Bay Buccaneers (6-10) | 38 | Indianapolis Colts (8-8) | 31 | - | - |
| 2021-11-28 | Atlanta Falcons (8-8) | 21 | Jacksonville Jaguars (5-11) | 14 | - | - |
| 2021-11-28 | Carolina Panthers (15-1) | 10 | Miami Dolphins (6-10) | 33 | - | - |
| 2021-11-28 | Tennessee Titans (3-13) | 13 | New England Patriots (12-4) | 36 | - | - |
| 2021-11-28 | Philadelphia Eagles (7-9) | 7 | New York Giants (6-10) | 13 | - | - |
| 2021-11-28 | Los Angeles Chargers (4-12) | 13 | Denver Broncos (12-4) | 28 | - | - |
| 2021-11-28 | Los Angeles Rams () | 28 | Green Bay Packers (10-6) | 36 | - | - |
| 2021-11-28 | Minnesota Vikings (11-5) | 26 | San Francisco 49ers (5-11) | 34 | - | - |
| 2021-11-28 | Cleveland Browns (3-13) | 10 | Baltimore Ravens (5-11) | 16 | - | - |
| 2021-11-29 | Seattle Seahawks (10-6) | 15 | Washington Commanders (9-7) | 17 | - | - |
| Totals | 0/0 | 0/0 | ||||
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