| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-09-16 | New York Giants (6-11) | 29 | Washington Commanders (4-13) | 30 | - | - |
| 2021-09-19 | New Orleans Saints (9-8) | 7 | Carolina Panthers (2-15) | 26 | - | - |
| 2021-09-19 | Cincinnati Bengals (9-8) | 17 | Chicago Bears (7-10) | 20 | - | - |
| 2021-09-19 | Houston Texans (10-7) | 21 | Cleveland Browns (11-6) | 31 | - | - |
| 2021-09-19 | Los Angeles Rams (10-7) | 27 | Indianapolis Colts (9-8) | 24 | - | - |
| 2021-09-19 | Denver Broncos (8-9) | 23 | Jacksonville Jaguars (9-8) | 13 | - | - |
| 2021-09-19 | Buffalo Bills (11-6) | 35 | Miami Dolphins (11-6) | 0 | - | - |
| 2021-09-19 | New England Patriots (4-13) | 25 | New York Jets (7-10) | 6 | - | - |
| 2021-09-19 | San Francisco 49ers (12-5) | 17 | Philadelphia Eagles (11-6) | 11 | - | - |
| 2021-09-19 | Las Vegas Raiders (8-9) | 26 | Pittsburgh Steelers (10-7) | 17 | - | - |
| 2021-09-19 | Minnesota Vikings (7-10) | 33 | Arizona Cardinals (4-13) | 34 | - | - |
| 2021-09-19 | Atlanta Falcons (7-10) | 25 | Tampa Bay Buccaneers (9-8) | 48 | - | - |
| 2021-09-19 | Dallas Cowboys (12-5) | 20 | Los Angeles Chargers (5-12) | 17 | - | - |
| 2021-09-19 | Tennessee Titans (6-11) | 33 | Seattle Seahawks (9-8) | 30 | - | - |
| 2021-09-19 | Kansas City Chefs (11-6) | 35 | Baltimore Ravens (13-4) | 36 | - | - |
| 2021-09-20 | Detroit Lions (12-5) | 17 | Green Bay Packers (9-8) | 35 | - | - |
| Totals | 0/0 | 0/0 | ||||
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